Dim (Diindolylmethane)

Food State with Calcium D - Glucarate (Hormones / Oestrogen Balance)
90 (100mg +) Capsules

DIM (Diindolylmethane) is a metabolite of a phytochemical known as Indole-3-Carbinol, it is 100% natural and is found in cruciferous vegetables like broccoli, cabbage and brussels sprouts. DIM is a revolution in hormone balance! Our 100% bioavailable and soy-free DIM supplements is a must-have for both women and men. It helps retaining hormonal balance by promoting your body's metabolism of too much oestrogen. For women, DIM relieves menopause symptoms such as, polycystic ovary syndrome, weight-loss, hot flashes, night sweats and hormonal acne. For men, DIM can help decrease excess oestrogen, support physical health, promote Prostate Health, provide more Energy, and Balance Weight. Comes in a Miron Glass Jar. NOTE: Please consult a medical doctor or qualified practitioner if you are using this product with the aim of Hormone Replacement Therapy, we are not qualified to give advice on this. 

£29.99 £24.99
In stock
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Ancient Purity presents a Food Based Diindolylmethane Supplement... Men and Women could both experience great results from supplementing with DIM. This is the ultimate unisex supplement! DIM is composed of a methane group with 2 indole groups attached to it. The main source of DIM in food is found in cruciferous vegetables which belong to the cabbage breed. Some of these include: broccoli, Brussels sprouts, cauliflower, cabbage and kale. These vegetables are well known as super healthy food choices and part of many individuals’ vegetable smoothie. Now you know that part of the reason they are so good for us is because of the effects of DIM. Cruciferous vegetables contain Glucobrassicin, which is a type of glucosinolate, which are natural components of many pungent plants that can aid ward off bacterial, fungal and viral infections in the intestines and other areas of your body. Several recent scientific studies have also indicated that a diet rich in cruciferous vegetables might lower your risk of certain chronic and severe health conditions where cells in a specific part of the body grow and reproduce uncontrollably. 

The digestion of glucobrassicin breaks down into indole-3-carbinol and thiocyanate when catalysed by the enzyme myrosinase, which is also present in cruciferous vegetables. Indole-3-carbinol quickly breaks down into DIM and other metabolites during the acid-mediated process of digestion. Cooking damages myrosinase, reducing DIM's bioavailability. Some bioavailability is retained because human intestines contain some myronsinase. Water also reduces the availability of DIM since glucobrassicin is water soluble. Ancient Purity recommends when eating for DIM, raw or low-temperature steaming (Preferably with Gravity Filtered Water) is the best option for preserving the bioavailability of glucobrassicin. Your body produces this important substance from cruciferous vegetables such as cauliflower, broccoli and Brussels sprouts. While reading this page you’ll discover that DIM provides many more hormone-related health benefits.

DIM (Diindolylmethane) – Information & Points to Research

  • Clean, Safe & Effective (Food Based).
  • Female Oestrogen Balance.
  • Male Testosterone Increase.
  • Increase Male Libido.
  • Menstrual Symptoms Management.
  • Healthy Prostate.
  • Hair Health.
  • Antioxidant Support.
  • Thyroid Health.
  • Support Muscle Mass.
  • Breast Health.
  • Fat Mobilisation & Burning Metabolism.
  • Calcium d Glucarate (Toxin Excretion).
  • The Power of Raw Cruciferous Vegetables.
  • Mood Booster.
  • Reduces Toxins Produced by your Body's Natural Metabolism.
  • Might Enhance Memory.
  • Healthy Weight Management.
DIM benefits

Optimise Oestrogen metabolism with DIM (Diindolylmethane)

The primary biochemical role of DIM (Diindolylmethane) is to modify the metabolism of oestrogen so that it produces more 2-hydroxy oestrogen metabolites. The most significant result of this change is a decrease in 16-hydroxyestrone (An endogenous steroidal oestrogen and a major metabolite of estrone and estradiol) production and an increase in 2-hydroxyestrone (The ‘good’ oestrogen) production. Optimal oestrogen metabolism in women means ample production of “good” oestrogen metabolites. These metabolites help lower the risk of major health issue and reduce symptoms of oestrogen over-stimulation or dominance-symptoms. Oestrogen decreases the frequency and severity of hot flushes by approximately 85%. Vaginal dryness is improved by oestrogen and by reducing symptoms of menopause oestrogen might improve sleep and overall well-being. In addition, oestrogen lowers the risk of post-menopausal bone fracture, including hip fracture.

These symptoms can include breast tenderness, rapidly growing uterine fibroid tumours, uterine cervix problems (as seen with abnormal PAP smears) and endometriosis, a painful condition caused by persistent uterine tissue growing in abnormal locations within the abdomen. The antioxidant activity of the “good” oestrogen metabolites may explain why oestrogen in women can slow the course of some age-related ailments. Scientists believe it is DIM's ability to influence the liver to make more of the "good" oestrogen and less of the "bad" that may play the biggest role in lowering the risk of breast issues. Female Weight-Loss from Hormone Balance... Higher levels of the “good” oestrogen metabolites are also important for sustaining fat-burning metabolism. “Good” metabolites support fat cells in releasing stored fat as well as helping to preserve the activity of the small amount of testosterone present in all women. This provides additional support for fat utilisation as well as support for mood and libido. The balance between these hormones can have a positive impact on fat loss and health, with high oestrogen causing PMS symptoms, weight-gain, and chronic tiredness. Although a natural occurrence, hormone fluctuations during the menstrual period also affect weight-loss in women. Healthy levels of testosterone in women may also help to reduce the symptoms of PMS.

Clean, Safe, Effective - 1 capsule daily

how to use DIM women

For Men - Testosterone, Muscle Mass, Fat-loss & Hair Health

Men can benefit from supplementing with DIM or gorging on raw cruciferous vegetables. We could be seeing an epidemic of low testosterone in men, you can research the possible causes yourself, but if you have unhealthy testosterone levels (Which can cause low moods and a poor libido) DIM could be a safe natural answer. It boosts testosterone production in the testes of males. Also, we've gone against the grain on the causes of male hair loss, and currently believe that a factor not considered enough is too much oestrogen in their body. On the dominance of oestrogen production, men can suffer from breast enlargement, hair loss, infertility and psychological errors. Men who wish to increase muscle mass with exercise may also want to take DIM. As mentioned above DIM naturally balances the oestrogen levels. As it boosts male testosterone it is popular with bodybuilders. Some consider it a "miracle drug". DIM might help cutting down fat layers from stubborn regions of the body, accelerating basal metabolism without decreasing toned muscle mass. High testosterone causes increased bone strength, improved lipid panels at a speedy rate. 

Men generally secrete oestrogen on the stimulation of aromatase enzyme that converts testosterone to estradiol. If the level of aromatase increases in blood, the oestrogen level shoots up and testosterone level starts diminishing which is not favourable. We also should mention that depending on lifestyle or underlying health factors, your body may have a higher concentration of the aromatase enzyme. Higher amounts of this enzyme mean that more of your testosterone will get converted into oestrogen, which both lowers testosterone levels and increases estradiol levels. High estradiol levels in men can reduce sperm production and make it more difficult to produce healthy sperm. 

DIM (Diindolylmethane)... Support your Active Lifestyle and Go Further

DIM benefits, DIM dosage

DIM (Diindolylmethane) Gives

Reducing Acne… While scientific research has not figured out yet why some people are more predisposed to acne than others and exactly causes it, there’s a wide range of factors which might contribute to this skin disorder, including your environment, the food you consume and genetics. DIM especially benefits those persons experiencing hormonal acne, the kind that occurs during periods of fluctuating hormones, such as menopause and adolescence. Both men and women have male hormones, such as testosterone. These hormones boost the production of sebum that contributes to the development of acne. Research indicated that DIM demonstrates antiandrogen activities. This effect might be useful in reducing sebum production in acne-prone males and females. On the market there’re numerous acne products, from facial scrubs to lotions, and acne soaps to creams. The big difference is that DIM promotes smoother skin from the inside.

Might Reduce PCOS Symptoms… Polycystic ovary syndrome (PCOS) is a hormonal disorder common among women of reproductive age. We can categorise sex hormones into two basic categories, female hormones like progesterone and oestrogen and male hormones such as testosterone. Both of these hormones are present in different quantities in males and female bodies. PCOS is a hormonal issue linked to the sex hormones. PCOS is characterised as well by the creation of many small fluid collections known as follicles which are positioned around the ovaries. This condition might lead to enlarged ovaries as well as not being able to release eggs regularly, weakening fertility. PCOS is responsible for insulin resistance, irregular menstrual periods, and hyperandrogenism (Too high testosterone amounts as well as other male hormones). Hyperandrogenism might cause symptoms such as the growth of more (thick) facial hair (hirsutism), hair loss and acne. Due to the antiandrogen effects and selective oestrogen activation of DIM, it might be helpful reducing symptoms of polycystic ovary syndrome.

Might Aid Regulate Inflammatory Responses… Scientific studies suggest an association between chronic inflammatory conditions and the proliferation and development of malignant cells in the body. In addition, a number of studies have been performed to establish exactly if DIM provides a potential effect on chronic and acute inflammation. In one rodent research, scientists studied DIM’s effects on mouse macrophages (A type of white blood cell that surrounds and kills microorganisms). This research indicated that DIM significantly decreased the production and release of interleukin, nitric oxide, prostaglandins, and several other pro-inflammatory substances. DIM also restrained the growth of protein levels of inducible nitric oxide synthase. We can conclude that DIM effectively reduced the release of pro-inflammatory agents in mice macrophages. This indicated that DIM might assist regulating inflammatory responses.

Let DIM Light you Up

Polycystic ovary syndrome (PCOS) is a hormonal disorder common among women of reproductive age. We can categorise sex hormones into two basic categories, female hormones like progesterone and oestrogen and male hormones such as testosterone. Both of these hormones are present in different quantities in males and female bodies. PCOS is a hormonal issue linked to the sex hormones. PCOS is characterised as well by the creation of many small fluid collections known as follicles which are positioned around the ovaries. This condition might lead to enlarged ovaries as well as not being able to release eggs regularly, weakening fertility. PCOS is responsible for insulin resistance, irregular menstrual periods, and hyperandrogenism (Too high testosterone amounts as well as other male hormones). Hyperandrogenism might cause symptoms such as the growth of more (thick) facial hair (hirsutism), hair loss and acne. Due to the antiandrogen effects and selective oestrogen activation of DIM, it might be helpful reducing symptoms of polycystic ovary syndrome

Calcium D-Glucarate Benefits

The beneficial compound known as Calcium D-glucarate is also present in Ancient Purity's DIM supplement. Calcium D-glucarate is a calcium salt produced of calcium and glucaric acid, a chemical compound found naturally in the body and in foods like apples, broccoli, and grapefruit. Calcium D-glucarate can aid preventing certain chronic and severe health issues where cells in a specific part of the body grow and reproduce uncontrollably. Preliminary research assumes that it decreases the body's levels of the hormone oestrogen, strengthening your defence against hormone-dependent malignant cells that might lead to severe chronic illness. In a nutshell, this compound supports liver detoxification, might reduce oestrogen levels, aids maintain already healthy cholesterol levels, and potentially inhibits certain health issues caused by malignant body cells. Calcium D-Glucarate Promotes Liver Detoxification…Calcium D-Glucarate plays a pivotal part in elimination of the substances your liver has prepared for excretion. To comprehend how calcium D-glucarate is beneficial for your hormones we should really explain liver metabolism. Please stick with me because the health of your live is everything in having brilliant hormones.

There are 2 steps in your liver to process the chemicals which need to be excreted by your body. These are referred to as Phase 1 and 2 liver detox. Following the first phase of detoxification harmful metabolites can be produced (Sometimes more harmful than what they initially were), which requires phase 2 detoxification to prepare them for elimination by the gut and kidneys. Hormones, medications, metabolic by-products, neurotransmitters, and various toxins are neutralised via the phase 2 liver detox. This occurs through a bodily process known as glucuronidation. This process takes toxins and binds them to a substance called glucuronic acid. This bound toxin is then excreted in bile to leave through a bowel movement or will be eliminated via the kidneys in the urine.You can read detailed scientific information on Calcium D-glucarate here. The liver manufactures a substance called glucuronic acid, which binds to toxins, including "bad" oestrogen, deactivating them. Glucuronic acid is an uronic acid which was isolated from urine first. It is present in numerous gums such as xanthan gum arabic, and Kombucha tea. Glucuronic acid is pivotal for the metabolism of microorganisms, animals and plants. The enzyme, beta-glucuronidase, can interfere, thus split the toxins of the glucuronic acid, reactivating them. Researchers have found that people with a high amount of that enzyme in their blood have an increased risk of various major health issues, particularly the hormone-dependent ones. Calcium D-G comes to the rescue by deactivating beta-glucuronidase, keeping the harmful oestrogens and other toxins bound to the glucuronic acid inactive.

Take the Natural Way with (Diindolylmethane) Doesn't Sound Natural... It is!

DIM ancient purity

Dim (Diindolylmethane)… Closing Thoughts

DIM (Diindolylmethane) is a naturally occurring compound present in Brassica vegetables such as Brussels sprouts, broccoli, kale, cabbage and cauliflower. DIM is currently intensively researched as a naturally occurring compound for the prevention and treatment of the condition in which some of the body's cells grow uncontrollably and spread to other parts of the body, infectious illnesses and immune deficiency issues due to its potent anti-malignant cells properties, immune modulating and anti-inflammatory activities. DIM is formed during the autolytic breakdown of glucobrassicin that are present in Brassica vegetables. The autolytic breakdown of glucobrassicin requires the catalytic reaction of the enzyme myrosinase which is endogenous to these plants and released upon the breaking of the cell wall of the plant.

DIM has powerful effects on oestrogen metabolism and is capable to retain the body relatively balanced (By preventing either significant increases or reductions in oestrogen). In small amounts, it can both inhibit the aromatase enzyme (And prevent the transformation of testosterone into oestrogen) and it can act on more potent forms of oestrogen and convert them into less potent forms; this conversion reduces the overall effects of oestrogen in the body. As most people cook or steam their DIM-boasting Brassica vegetables before consuming them, most of the DIM will be eliminated. This supplement ensures your body always has the correct DIM levels, and believe me, we all need it! 

“The soybean itself is a notably inauspicious staple food; it contains a whole assortment of "anti-nutrients" - compounds that actually block the body's absorption of vitamins and minerals, interfere with the hormonal system, and prevent the body from breaking down the proteins of the soy itself.” ― Michael Pollan

Experience Hormone Balance & More with DIM - Order Today

DIM (Diindolylmethane) 100% Bio-Available, ultra-powerful 1st choice in balancing hormones for Men and Women.
  • DIM (Diindolylmethane) (soy-free, from sunflower lecithin)
  • Alfalfa.
  • Calcium D Glucarate.
  • Phosphatidyl Choline.
  • Vegetable Cellulose - Capsule.
  • Take 1 capsule daily with food or as directed by your practitioner. Do not exceed the recommended daily intake.

NOTE: Before trying any supplement, talk to your doctor. DIM may reduce the effectiveness of some medications. Your doctor can decide whether you need to switch to a different drug while taking DIM. They can also help you figure out what amount is right for your needs.

  • Brand: Ancient Purity.
  • Size: 90 Capsules.
  • Container: Miron Glass Jar.
  • Storage: Keep in a cool dry place, keep out of reach of children.
  • Estimated shelf life from purchase: 2 years.

Scientific Articles

Memorial Sloan Kettering Cancer Center - Diindolylmethane

PMC Labs - Diindolylmethane Modulates Estrogen Metabolism in Patients with Thyroid Proliferative Disease: A Pilot Study

NCBI Resources - A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen

Oxford Academic - Diindolylmethane (DIM): a nutritional intervention and its impact on breast density in healthy BRCA carriers. A prospective clinical trial

Supporting Scientific Research

  1. Meilahn EN. De Stavola B. Allen DS. Fentiman I. Bradlow HL. Sepkovic DW. Kuller LH. Do urinary estrogen metabolites predict breast cancer? Follow up of the Guernsey III cohort. Br J Cancer. 1998;78:1250–1255.
  2. Garikapaty VP. Ashok BT. Chen YG. Mittelman A. Iatropoulos M. Tiwari RK. Anti-carcinogenic and anti-metastatic properties of indole-3-carbinol in prostate cancer. Oncol Rep. 2005;13:89–93.
  3. Zeligs MA. Sepkovic DW. Manrique C. Macsalka M. Williams DE. Bradlow HL. Absorption-enhanced 3,3′-diindolylmethane: human use in HPV-relaed, benign and pre-cancerous conditions. Proc Am Assoc Cancer Res. 2002;43 3198 (abstract).
  4. Ciska E, Verkerk R, Honke J. Effect of boiling on the content of ascorbigen, indole-3-carbinol, indole-3-acetonitrile, and 3,3′-diindolylmethane in fermented cabbage. J Agric Food Chem. 2009;57(6):2334–2338. doi: 10.1021/jf803477w.
  5. Ahmad, A.  et al.  (2010) Anticancer properties of indole compounds: mechanism of apoptosis induction and role in chemotherapy. Curr. Drug Targets, 11, 652–666.
  6. Dalessandri, K.M.  et al.  (2004) Pilot study: effect of 3,3’-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer. Nutr. Cancer, 50, 161–167.
  7. Gregory, A.R.  et al.  (2008) Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3’-diindolylmethane in healthy subjects. Cancer Epidemiol. Biomarkers Prev., 17, 2619–2624.
  8. Fowke, J.H.  et al.  (2000) Brassica vegetable consumption shifts estrogen metabolism in healthy postmenopausal women. Cancer Epidemiol. Biomarkers Prev., 9, 773–779.

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