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Choline Citrate (Perque) 250ml

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Choline Citrate (Perque) 250ml

Choline Citrate by Perque, for Cognitive and Mood and general foundation of good health. Masterfully betters cell communication, nerve impulses and liver bile detox. Giving higher physical performance, mental endurance, and easy available energy. A patented enhanced magnesium uptake system.

Availability: In stock

£49.99

Details22

PERQUE Choline Citrate combines both choline and citrate. This is important because citrate activates choline as it energizes and alkalizes the cell. Choline Citrate replenishes choline stores quickly and effectively, improving endurance and performance. 

Athletes, in particular, can benefit from Choline Citrate supplementation. Neurotransmitters that are dependent upon choline, such as acetylcholine, can affect physical performance. Studies demonstrate that exercise significantly reduces Choline levels. Studies have indicated that Choline deficiency is linked to neurological disorders.

Perque Choline Citrate comes in a liquid form to guarantee optimum absorption and purity. The commonly used form of choline, choline bitartrate, contains cornstarch and may contain reactive or irritative antigens. PERQUE Choline Citrate is contaminant free, more bio-available than tablets or capsules and convenient. Activated Choline has many unique benefits.

Choline Citrate

  • Essential for Athletes.
  • Choline Citrate can increase energy for individuals who fatigue easily.
  • Choline is necessary for the proper transport and metabolism of fats. Without Choline, fat accumulates in the liver. Choline Citrate increases bile acid production for gallbladder health and supports weight loss.
  • Choline Citrate enhances liver detoxification, helping it remove toxic waste products from the bloodstream.
  • Choline is essential for the transmission of nerve impulses and memory function.
perque UK

Perque's unique Choline Citrate

PERQUE Choline Citrate can increase magnesium uptake. No other form of choline has this benefit. PERQUE Choline Citrate is essential for people who have a block in the primary calcium-magnesium ATPase uptake system, such as individuals with chronic fatigue syndrome or fibromyalgia.

This is the pathway that creates energy and takes magnesium into cells. The caveat is that the pathway requires adequate energy to work efficiently.

When stress or illness compromises the immune system, and when diet, toxins, or immune reactions cause excess cellular acidity (metabolic acidosis), magnesium uptake cannot take place, and this important pathway is impaired.

Bypassing the energy pathway, PERQUE Choline Citrate and PERQUE Mg Plus Guard together create a neutral charge to carry magnesium effortlessly through the cell membrane. 

Those who take magnesium but still show signs of magnesium deficiency need PERQUE Choline Citrate. Cramps, muscle twitches, and spasms that persist even when magnesium is supplied indicate uptake impairment. PERQUE Choline Citrate is specifically designed to facilitate magnesium uptake for everyone. 

perque Choline Citrate UK

Choline Functions

Choline is not actually a vitamin or mineral, it's an organic water-soluble compound that's often grouped with B vitamins, because it has similar properties and functions. It helps in regulation of many body functions.

Fat Transport & Metabolism
Choline is necessary for turning fat and cholesterol into lipoproteins called very low density lipoproteins (VLDL). It also helps transport VLDL into the bloodstream and to the extrahepatic tissues, preventing fat and cholesterol from accumulating in the liver.

DNA synthesis
According to a study published in the journal Mutation Research, choline is a major source of methyl groups necessary for the synthesis of S-adenosylmethionine, which is needed for epigenetic marking of DNA and histones.
Nervous system function — Choline is a precursor for acetylcholine, a neurotransmitter involved in various neuronal functions, including muscle control, circadian rhythm and memory.

Cell structure 
Choline is necessary for the synthesis of phosphatidylcholine and sphingomyelin, which are phospholipids that help maintain the structural integrity of the cell membranes.

Cell Messaging 
The phospholipids that are synthesized from choline also act as a precursor for the intracellular messenger molecules, diacylglycerol and ceramide.

Body & Mind. 
In a recent study, researchers examined random, placebo-controlled trials of choline deficiency in cognitive disorders. The reviewers found that choline had significant beneficial effects on memory function and behaviour. In another study, researchers found that choline supplementation improved subjects’ memory, especially in Alzheimer’s patients. Choline helps the body as well as the mind. Studies show that in trained athletes, physical exertion can deplete choline stores by as much as 40%. In one such study, researchers concluded that “Thus, the reductions in plasma choline associated with strenuous exercise may reduce acetylcholine release, and could thereby affect endurance or performance.”

Choline under Study during pregnancy

Studies have underscored the importance of Choline during pregnancy During pregnancy, the mother provides high amounts of Choline across the placenta to the fetus. The effect of this nutrient on fetal brain development occurs during embryonic days 11 - 17.

Studies have shown that higher dietary choline intake during this sensitive window in fetal development may lead to enhanced memory performance in later life.

Choline is also responsible for improving the signaling mechanisms involved in the formation of new blood vessels in the placenta. Plus, it may help inhibit the pathological precursors of preeclampsia, as well as mitigate the effects of alcohol exposure to the fetus.

Moreover, Choline deficiency during pregnancy may put the baby at risk of neural tube defect and orofacial cleft. In the USA, pregnant women who consume only 150mg of Choline daily are 4 x more likely to have a baby with neural tube defects, while their risk for having a baby with orofacial cleft increases by up to 1.7%.

Scientific Evidence

perque choline

1.Fioravanti M, Yanagi M: Cytidinediphosphicholine (CDP choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Chochrane Database Syst. Rev 2005 Apr 18; (2):CD000269. 2.Canty DJ, Zeisel SH: Lecithin and choline in human health and disease. Nutr Reviews 1994; 52: 327- 339. 
3. Zeisel SH. Choline: needed for normal development of memory. J Am Coll Nutr 2000 Oct; 19 (5 Suppl):528S-531S. 
4. Zeisel SH. Choline: critical role during fetal development and dietary requirements in adults. Annu Rev Nutr 2006;26:229-50. 5. Spector SA, Jackman MR, Sabounjian LA, Sakas C, Landers DM, Willis VVT: E ect of choline supplementation on fatigue in trained cyclists. Med Sci Sports Exerc 1995 May; 27(5): 668-73. 

Experience Perque's Unique Choline Citrate - Order Today

perque UK choline Citrate

Details44

  • Choline Citrate.

Details44

  • As a dietary supplement‚ take one (1) teaspoon in juice or water or as directed by your health professional.

Details44

  • Brand: Perque.
  • Form: Liquid.
  • Quantity: 250ml.
  • Container: Glass bottle.
  • Storage: Keep in a cool dry place, keep out of reach of children.
  • Estimated shelf life from purchase: 1 - 2 years.

Details60

1.Fioravanti M, Yanagi M: Cytidinediphosphicholine (CDP choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Chochrane Database Syst. Rev 2005 Apr 18; (2):CD000269. 2.Canty DJ, Zeisel SH: Lecithin and choline in human health and disease. Nutr Reviews 1994; 52: 327- 339. 3. Zeisel SH. Choline: needed for normal development of memory. J Am Coll Nutr 2000 Oct; 19 (5 Suppl):528S-531S. 4. Zeisel SH. Choline: critical role during fetal development and dietary requirements in adults. Annu Rev Nutr 2006;26:229-50. 5. Spector SA, Jackman MR, Sabounjian LA, Sakas C, Landers DM, Willis VVT: E ect of choline supplementation on fatigue in trained cyclists. Med Sci Sports Exerc 1995 May; 27(5): 668-73. 6. Conlay LA, Sabounjian LA, Wurtman RJ: Exercise and neuromodulators: choline and acetylcholine in marathon runners. Int J Sports Med 1992 Oct; 13 Suppl 1:S141-2. 7. Secades JJ, Lorenzo JL. Citicoline: Pharmacological and clinical review, 2006 update. Methods Find Exp. Clin Pharmacol. 2006 Sep;28 Suppl B:1-56.

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