Liposomal Melatonin

4.5mg per serving (Liposomal) Sleep Jet Lag / Mood / Immunity / Hair Topical
30ml (1.01 fl. oz.)

Liposomal Melatonin Spray. Each serving contains 4.5 mg of the highest quality Melatonin in a Liposomal delivery system (Transporting substances into the body effectively) A Liposomal liquid delivery system allows for flexible, convenient dosing of Melatonin. Melatonin’s chemical name is N-acetyl-5-methoxytryptamine. It is a hormone released by our brain’s pineal gland, which is positioned a lilt bit above tour “middle brain”. Melatonin is a small hormone about a pea’s size. This important hormone’s job is setting our “sleep-wake cycles” and for keeping our bodies’ circadian rhythm, so long as we take the correct dosage of Liposomal Melatonin. Its release and synthesis are stimulated by darkness and light suppresses it. Our circadian rhythm is subject slang for our own person internal clocks that run on a 24-hour schedule, just like a day. Our internal clocks play a significant part in when we fall asleep and wake up. This means that regulating our internal clocks is essential for dealing with sleep issues. When there is darkness, our bodies produce more Melatonin, when there’s light, its production reduces. This is a Clean, Safe Effective Melatonin Supplement.

£25.99 £21.66
In stock
EU/World Prices

Ancient Purity presents Liposomal Melatonin. New research indicates that Melatonin (N-acetyl-5-methoxytryptamine) does much more than help some people sleep better. Exciting studies show that Melatonin’s multifaceted effects may improve treatment outcomes and extend lives. Additional applications of Liposomal Melatonin include guarding the nervous system against degenerative health problems debilitating headaches. Melatonin is secreted from the pineal gland deep inside the brain. For more than a quarter-century, scientists have been intrigued by Melatonin’s ability to coordinate the body’s physiological rhythms that help set the brain’s biological clock. 

The principal factor affecting Melatonin is light, which inhibits the secretion of this hormone. Darkness has the opposite effect from light, resulting in signalling to the pineal gland to increase Melatonin secretion. The normal cycles of Melatonin production are altered due to factors including ageing, medications, and light exposure at night. While the long-term health effects of disrupted Melatonin secretion are not yet fully known, some scientists have suggested that years of working nights could lead to adverse effects—even serious disease. Fortunately, Melatonin supplements can safely and effectively restore balance to the body’s circadian rhythm of this important hormone—helping achieve a restful night’s sleep and keeping your biological clock ticking throughout a long, healthy lifespan.

Liposomal Melatonin – Information & Points to Research

  • Clean, Safe & Effective Supplement.
  • Liposomal Delivery for Full Absorption.
  • 4.5mg of Melatonin per Serving.
  • Promotes Restful Sleep.
  • Supports Brain Health.
  • Balance Immune System.
  • Combats Jet Leg.
  • Energy over Daytime Fatigue.
  • Supports Healthy Vision.
  • May Help Control Eye Pigmentation & Regulate the Amount of Light Reaching the Photoreceptors, Protecting Eyes from Damage.
  • May Decrease Symptoms of SAD.
  • Fights Unwanted Menopause Symptoms.
  • Helps Morning Awakening.
  • Might Ease Anxiety Before & After Surgery.
can i buy melatonin in the UK

Liposomal Melatonin Spray - Sleep Support & So Much More...

Liposomal Melatonin Spray is a dietary supplement to support normal sleep. Each serving contains 4.5 mg of the highest quality Melatonin in a Liposomal delivery system

Melatonin Health Benefits

Most-likely the most known health benefit of Melatonin is that it might promote healthy sleep. For millions of persons all around the world, Liposomal Melatonin might be the solution to preventing another horrible night’s sleep. We all understand that avoiding sleep deprivation is extremely important for staying healthy and energised, in part due to it helping to ward off both chronic and acute health issues. This handy spray bottle of Liposomal Melatonin can be used easily to aid getting some decent sleep and to avoid jet lag. The hormone Melatonin produces a number of health benefits in terms of your immune system. It's a powerful antioxidant and free radical scavenger that helps combat inflammation. In fact, Melatonin is so integral to your immune system that a lack of it causes your thymus gland which is a key component of your immune system. Melatonin may even play a role in slowing the ageing of your brain. 

It also binds to receptors in the body and can help you relax. Melatonin binds to receptors in the brain to help reduce nerve activity. In the eyes, it can help reduce dopamine levels, a hormone that helps you stay awake. What is Liposomal Melatonin used for when taken as a food supplement? The answer that most people give is the usage of it as a natural sleep aid. But did you know Liposomal Melatonin has several other health-benefits as well? Let’s have a look at these.

Liposomal Melatonin Available at Ancient Purity

Melatonin, N-acetyl-5-methoxytryptamine, Liposomal Melatonin, Melatonin Spray, Melatonin Hormone, Insomnia, Sleeplessness, Jet Lag, Sleep Disorder, High Blood Pressure, Circadian Rhythm, Heart Disease, Cardiovascular Health, Fatigue, Immune System, Head Ache, Reproductive Health, Menopause Symptoms, Bladder, Depression, SAD, Eye Health

Melatonin Gives

Reduces Inconvenient Menopause Symptoms… Liposomal Melatonin has shown to reduce sleeplessness experienced during menopause. In a scientific research of perimenopausal (Around menopause) and menopausal females ages 43 to 63, within 6 months of daily Liposomal Melatonin supplementation, the majority of the females reported a general enhancement of mood and a drastic mitigation of low mood. The results of this research appear to indicate that Liposomal Melatonin supplementation among menopausal and perimenopausal ladies might lead to recovery of thyroid functions and pituitary (The major endocrine gland) which is more in the direction of a youthful pattern of regulation.

Might Decrease Symptoms of SAD…Seasonal affective disorder (SAD), also known as seasonal depression, is a condition affecting up to 10% of the population worldwide. You can read a scientific report on SAD here. This kind of seasonal low mood is related to the seasons’ changes and strikes every year around the same time, with signs typically appearing in late autumn to the beginning of winter. Some scientific studies indicate that it could be connected to changes in our circadian rhythms caused by changes of seasonal light. You can read a scientific report on SAD and disorder of circadian rhythms here.  Because Liposomal Melatonin plays a part in circadian rhythm regulating, small doses are mostly used to reduce SAD’s symptoms. According to one research in 65 persons, circadian rhythm’s alterations revealed to contribute to SAD, but taking small Liposomal Melatonin sprays daily was effective at decreasing symptoms.

Liposomal Melatonin - Supporting You On Through the Night

Liposomal Melatonin is rich in antioxidants
 Liposomal Melatonin has shown to reduce sleeplessness

Melatonin Keeps Giving

Might Support Healthy Vision… Liposomal Melatonin is rich in antioxidants which might assist preventing the harming of cells and retain healthy eyes. In fact, scientific studies suggest that Melatonin could be helpful in treating issues like glaucoma and age-related macular degeneration. You can read here about the role of Melatonin in the eye and ocular dysfunctions. In a research in 100 participants with age-related macular degeneration (AMD), supplementing with 3 mg of Liposomal Melatonin for 6 to 24 months assisted protecting the retina, delay age-related harm and preserve visual clarity.

There are even more Melatonin health benefits such as relieving gastroesophageal reflux disease, increase human growth hormone (HGH) levels, Relieve bladder dysfunction and promote cardiovascular health. We recommend doing some research on the other health-benefits provided by Liposomal Melatonin.

Melatonin for Hair

Melatonin has strong antioxidant properties (Fischer et al 2012) making it a prime candidate in combating the oxidative stress associated with general hair loss and androgenic alopecia (AGA). Human hair follicles are able to synthesize melatonin and express melatonin receptors (Kobayashi et al, 2005; Fischer et al, 2008). Studies have shown that these receptors are all in the hair sheath, which aids in the regulation of hair growth and stabilisation of the hair shaft. Further, it has been noted that melatonin can interact with androgen and estrogen receptor mediated signalling pathways. This observation may be highly relevant, given the role of androgens and estrogens in hair growth control (Fischer et al, 2008). Based on the hypotheses on melatonin's effect on hair growth, a topical solution of 0.0033% melatonin was developed by ASATONA AG (Zug, Switzerland). Several studies were conducted on behalf of this company to investigate the effect of melatonin on hair loss and results showed treatment to be well tolerated and effective (Lorenzi and Caputo, 2003; Macher, 2003). However, conclusions drawn from these results are limited because some observations were not placebo controlled and were based on subjective questionnaires for the patients. 

Women with diffuse alopecia experienced an increase in frontal hair counts. Fischer et al (2004) also conducted a study on 40 women with diffuse alopecia or AGA. A 1% melatonin-alcohol solution was applied once daily on the scalp over 6 months. The results showed an increase in anagen hair growth phase in the occipital scalp areas in women with AGA. Their frontal hair counts were unaffected. However, women with diffuse alopecia experienced an increase in frontal hair counts. This effect might be interpreted as induction of hair growth by prolongation of the anagen phase (Nixon et al 1993). The value of these findings may be improved by repeating similar studies on larger populations and for longer periods. Moreover, additional hair growth parameters would have to be included before firm conclusions can be drawn on the efficacy of topical melatonin in the management of hair loss (Nixon et al 1993). References in Section.

Support Sleep Naturally with Liposomal Melatonin

Liposomal Melatonin Spray The hormone melatonin produces a number of health benefits

Improve & Balance Melatonin Production Naturally

Two common environmental "noise" factors that can make sleep elusive are light pollution and temperature. The following suggestions can improve your sleep hygiene and help you optimise your melatonin production. 

Avoid watching TV or using your computer in the evening, at least an hour or so before going to bed. These devices emit blue light, which tricks your brain into thinking it's still daytime. Normally your brain starts secreting Melatonin between 9 and 10 pm, and these devices emit light that may stifle that process.

Make sure you get BRIGHT sun exposure regularly. Your pineal gland produces Melatonin roughly in approximation to the contrast of bright sun exposure in the day and complete darkness at night. If you are in darkness all day long, it can't appreciate the difference and will not optimise your Melatonin production.

Sleep in complete darkness, or as close to it as possible. Even the slightest bit of light in your bedroom can disrupt your biological clock and your pineal gland's Melatonin production. Even the tiniest glow from your clock radio could be interfering with your sleep, so cover your radio up at night or get rid of it altogether. Move all electrical devices at least three feet away from your bed. You may want to cover your windows with drapes or blackout shades.

Install a low-wattage yellow, orange or red light bulb if you need a source of light for navigation at night. Light in these bandwidths does not shut down Melatonin production in the way that white and blue bandwidth light does. Salt lamps are handy for this purpose.

Upgrade Your Sleep Setting & Supplement with Melatonin

Melatonin production natural

Improve & Balance Melatonin Production Naturally Continued

Keep the temperature in your bedroom no higher than 70 degrees F. Many people keep their homes too warm (Particularly their upstairs bedrooms). Studies show that the optimal room temperature for sleep is between 60 to 68 degrees. 

Take a hot bath 90 - 120 minutes before bedtime. This increases your core body temperature, and when you get out of the bath it abruptly drops, signaling your body that you are ready to sleep.

Avoid using loud alarm clocks. Being jolted awake each morning can be very stressful. If you are regularly getting enough sleep, you might not even need an alarm.

Get some sun in the morning, if possible. Your circadian system needs bright light to reset itself. Ten to 15 minutes of morning sunlight will send a strong message to your internal clock that day has arrived, making it less likely to be confused by weaker light signals during the night. More sunlight exposure is required as you age.

Be mindful of electromagnetic fields in your bedroom. EMFs can disrupt your pineal gland and its melatonin production and may have other negative biological effects as well. A gauss meter is required if you want to measure EMF levels in various areas of your home.

Get into a Natural Cycle with Melatonin

Liposomal Melatonin

Melatonin & Light

In humans as with all mammals, your biological clock resides in the suprachiasmatic nucleus of your brain (SCN), which is part of your hypothalamus. Based on signals of light and darkness, your SCN tells your pineal gland2 when it's time to secrete Melatonin. Light comes in through your eyes and travels up your optic nerves to the SCN, which is exquisitely sensitive to cycles of light and darkness.  When you turn on a light at night, you immediately send your brain misinformation about the light-dark cycle. The only thing your brain interprets light to be is day. Believing daytime has arrived, your biological clock instructs your pineal gland to immediately cease its production of Melatonin. When we are exposed to light, it triggers a nerve pathway from the eye’s retina to a brain area called the hypothalamus. This is the location of the suprachiasmatic nucleus (SCN), and the pineal gland’s turning is initiated by the SCN. As soon as the SCN turns the pineal gland on, it commences the production of Melatonin which is next released into our bloodstreams.

The precursor to the hormone Melatonin is known as serotonin (The famous feel good hormone), a neurotransmitter which is derived from tryptophan (An amino acid). A chemical that is occurring naturally known as acetylserotonin functions as the intermediary. Acetylserotonin is produced by serotonin, which is then transformed into Melatonin. Whether you have the light on for an hour or for just a second, the effect is the same — and your Melatonin pump doesn't turn back on when you flip the light back off. Since humans evolved in the glow of firelight, the yellow, orange and red wavelengths don't suppress Melatonin production the way white and blue wavelengths do. In fact, the range of light that inhibits Melatonin is fairly narrow — 460 to 480 nm. If you want to protect your Melatonin, when the sun goes down you would shift to a low wattage bulb with yellow, orange, or red light. Ancient Purity suggests using a salt lamp illuminated by a 5-watt bulb in this colour range.

Melatonin's Effects Will Support a Healthy, Active Lifestyle

how to take melatonin

Liposomal Melatonin… Closing Thoughts

Well, let’s try to explain Melatonin simply... Melatonin’s chemical name is N-acetyl-5-methoxytryptamine. It is a hormone released by our brain’s pineal gland, which is positioned a lilt bit above tour “middle brain”. Melatonin is a small hormone about a pea’s size. This important hormone’s job is setting our “sleep-wake cycles” and for keeping our bodies’ circadian rhythm, so long as we take the correct dosage of Liposomal Melatonin. Its release and synthesis are stimulated by darkness and light suppresses it. Our circadian rhythm is subject slang for our own person internal clocks that run on a 24-hour schedule, just like a day. Our internal clocks play a significant part in when we fall asleep and wake up. This means that regulating our internal clocks is essential for dealing with sleep issues. When there is darkness, our bodies produce more Melatonin, but when there’s light, Melatonin’s production reduces. This is why blind people or persons working in the night can experience difficulties with maintaining normal Melatonin levels. For anyone, not getting enough exposure to daylight, or exposure in the evening to bright lights, can disrupt their bodies’ normal Melatonin cycles. 

The hormone Melatonin is also pivotal to women’s reproductive health as Liposomal Melatonin plays a main part in controlling the timing and the freeing of reproductive female hormones. It aids deciding when a female begins to menstruate, the menstrual cycles’ regularity and duration, as well as when a female stops menstruating entirely (menopause). Scientists believe that the production of Melatonin reduces as we get older and that young kids have the highest Melatonin levels (Especially during night time, which is the reason why children typically sleep deeper and longer than adults). Should this be true, then it probably explains why older persons don’t tend to sleep as well as they did when they were children. So, supplementing with Liposomal Melatonin might help you sleep better, especially when you have chronically low levels of this hormone. This Supplement is often a game changer, maybe it will be for you.

 “I've always envied people who sleep easily. Their brains must be cleaner, the floorboards of the skull well swept, all the little monsters closed up in a steamer trunk at the foot of the bed.” - David Benioff, City of Thieves

Experience Restful Sleep & Awakening with Liposomal Melatonin - Order Today

 Melatonin, N-acetyl-5-methoxytryptamine, Liposomal Melatonin, Melatonin Spray, Melatonin Hormone, Insomnia, Sleeplessness, Jet Lag,   melatonin spray liposomal
  • Melatonin.

Other Ingredients: glycerin, water, sunflower lecithin, oleic acid polyglyceride, citric acid, xanthan gum, orange oil, and rosmarinic acid (A hydroxylated compound frequently found in herbal plants and is mostly responsible for anti-inflammatory and anti-oxidative activity).

  • Shake well before each use.
  • Hold nozzle 1 inch from the mouth and spray 3 times and swallow, or as directed by your healthcare practitioner. Do not exceed recommended daily intake.

NOTE: Consider beginning with a small dose - 0.25mg or 0.5mg increasing from there. Higher amounts like 3mg could make you more wakeful instead of sleepier, adjust the amount carefully.

WARNING: 

  • This product should not be taken by adolescents, pregnant or lactating women, persons taking cortisone, or persons with kidney disease.
  • Consult your physician if taking medications for sleep, anxiety or if on any anti-coagulant, antidepressant, antipsychotic or anti-hypertensive drugs. Because 
  • Melatonin Spray might affect your sleep-wake cycle so avoid consuming it with caffeine or alcohol. These can interfere with your circadian rhythm and your natural Melatonin production. 
  • Birth control pills might cause your body to begin creating more Melatonin, so taking a supplement could push your levels into an unhealthy range. 
  • You should also avoid taking Melatonin if you take corticosteroids to suppress your immune response for conditions such as rheumatoid arthritis or lupus.
  • Brand: Da Vinci Labs.
  • Size: 30ml (1.01 fl. oz.).
  • Container: Glass bottle.  
  • Storage: Keep cap on when not using, can be put in the fridge.
  • Estimated shelf life from purchase: 1 - 2 years.

Scientific Articles

Sleep Foundation - Melatonin and Sleep

ACS Chemistry for Life - The Science of Sleep

Johns Hopkins Medicine - Melatonin for Sleep: Does It Work?

Supporting Scientific Research

  1. Kilic E., Ozdemir Y.G., Bolay H., Kelestimur H., Dalkara T. Pinealectomy aggravates and melatonin administration attenuates brain damage in focal ischemia. J. Cereb. Blood Flow Metab. 1999;19:511–516.
  2. Lee M.Y., Kuan Y.H., Chen H.Y., Chen T.Y., Chen S.T., Huang C.C., Yang I.P., Hsu Y.S., Wu T.S., Lee E.J. Intravenous administration of melatonin reduces the intracerebral cellular inflammatory response following transient focal cerebral ischemia in rats. 2007.
  3. Nakade O., Koyama H., Ariji H., Yajima A., Kaku T. Melatonin stimulates proliferation and type I collagen synthesis in human bone cells in vitro. J. Pineal Res. 1999;27:106–110.
  4. Scheer F.A., Van Montfrans G.A., Van Someren E.J., Mairuhu G., Buijs R.M. Daily night-time melatonin reduces blood pressure in male patients with essential hypertension. Hypertension. 2004;43:192–197.
  5. Bliwise DL, Ansari FP. Insomnia associated with valerian and melatonin usage in the 2002 National Health Interview Survey. Sleep. 2007;30:881–884.
  6. Seelig AD, Jacobson IG, Smith B, Hooper TI, Boyko EJ, Gackstetter GD, Gehrman P, Macera CA, Smith TC. Sleep patterns before, during, and after deployment to Iraq and Afghanistan. Sleep. 2010;33:1615–1622.
  7. Wagner J, Wagner ML, Hening WA. Beyond benzodiazepines: alternative pharmacologic agents for the treatment of insomnia. Ann Pharmacother. 1998;32:680–691. doi: 10.1345/aph.17111.
  8. Pandi-Perumal S, Srinivasan V, Spence D, Cardinali D. Role of the melatonin system in the control of sleep: therapeutic implications. CNS Drugs. 2007;21:995–1018. doi: 10.2165/00023210-200721120-00004.
  9. Middleton B, Arendt J, Stone BM. Complex effects of melatonin on human circadian rhythms in constant dim light. J Biol Rhythms. 1997;12:467–477.
  10. Gorfine T, Assaf Y, Goshen-Gottstein Y, Yeshurun Y, Zisapel N. Sleep-anticipating effects of melatonin in the human brain. Neuroimage. 2006;31:410–418. doi: 10.1016/j.neuroimage.2005.11.024.
  11. Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS One. 2013;8:e63773. doi: 10.1371/journal.pone.0063773.

References for Hair Section

  1. Fischer, T.W., Andrzej Slominski, Tobin, D.J. and Paus, R., Melatonin And The Hair Follicle, Journal of Pineal Research, 2008 Jan; 44(1): 1-15
  2. Fischer, T.W., Burmeister, G., Schmidt, H.W. and Elsner, P., Melatonin Increases Anagen Hair Rate In Women With Androgenic Alopecia Or Diffuse Alopecia: Results Of A Pilot Randomized Controlled Trial, Br J Dermatol 2004 Feb; 150(2):41-5
  3. Fischer, T.W., Trüeb, R.M., Hanggi, G, Innocenti, M. and Elsner, P., Topical Melatonin For Treatment Of Androgenic Alopecia, Int J Trichol, 2012; 4(4):236-45
  4. Kobayashi. H., Kromminga. A., Dunlop, T.W.., Tychsen, B., Conrad, F. and Suzuki N, A Role Of Melatonin In Neuroectodermal-Mesodermal Interactions: The Hair Follicle Synthesizes Melatonin And Expresses Functional Melatonin Receptors. FASEB J.2005; 19:1710-2.
  5. Lorenzi. S. and Caputo, R. (2003) Melatonin Cosmetic Hair Solution: Open Study Of The Efficacy And The Safety On Hair Loss (Telogen) Control And Hair Growth (Anagen) Stimulation. MEL-COS-ASO1. Data on file. Asatona AG, Switzerland.
  6. Macher, J.P. (2003) Pharmacokinetics And Clinical And Biological Tolerability Of Repeated Topical Application Of A Melatonin- Containing Cosmetic Hair Solution In Healthy Female Volunteers. A Double-Blind, Placebo-Controlled, Cross Over Design Study. Clinical Study Report. MEL-COS-1. Data on file. Asatona AG, Switzerland.
  7. Nixon, A.J., Choy, V.J. and Parry, A.L., Fiber Growth Initiation In Hair Follicles Of Goats Treated With Melatoni, J Exp Zool 1993; 267:47–56.

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