Vitamin B12 | Activated™

Perque Activated™ B-12 Guard - Activated Hydroxocobalamin for Energy, Brain & Nervous System Support

• Energy, Endurance & Fatigue Support - Vitamin B12 plays a central role in red blood cell formation and cellular energy production. This activated form is widely used to support stamina, reduce weakness and help combat persistent tiredness.
• Sublingual “Oral Injection” Delivery - Delivered as a lozenge for absorption through the oral mucosa, bypassing low stomach acid and intrinsic factor issues that commonly impair B12 uptake.
• Brain, Nerve & Cognitive Function - B12 is essential for healthy nerve function and brain chemistry. By supporting SAMe activity, it contributes to mental clarity, focus and the maintenance of healthy neurotransmitter balance.
• Superior Hydroxocobalamin Form - Hydroxocobalamin is a parent form of B12 with the longest half life in the body, allowing sustained availability and conversion into active forms as needed, rather than forcing a single pathway.

Vitamin B12 deficiency is far more common than many realise. Modern diets, chronic stress, ageing, low hydrochloric acid and reduced intrinsic factor production all interfere with absorption. Even diets that appear sufficient often fail to deliver usable B12 at the cellular level.

Perque Activated B-12 Guard uses hydroxocobalamin, a form shown to remain active in the body longer than other B12 forms and effectively raise serum B12 levels. Unlike cyano forms or isolated methyl B12, hydroxocobalamin allows the body to regulate conversion naturally into methylcobalamin and adenosylcobalamin as required, supporting balance rather than forcing chemistry.

The lozenge format allows B12 to be absorbed directly, earning its reputation as an “oral injection”. Studies on this formulation have demonstrated uptake approaching that of injectable B12, without needles or clinical intervention. This makes it particularly valuable for individuals with digestive challenges, chronic fatigue, neurological demand or increased stress load. Perque Activated B-12 Guard contains no inactive ingredients and is designed for daily use. One lozenge per day is sufficient to support energy, endurance and nervous system function in a clean, efficient and reliable way.

Q: Why do I need Vitamin B12?
A: Vitamin B12 is essential for life. It is required for the formation of healthy red blood cells, the synthesis of DNA, and the proper functioning of the brain and nervous system. It plays a central role in energy production, neurological signalling, and cellular repair. Without adequate B12, oxygen delivery to tissues declines, nerve insulation deteriorates, and cognitive performance can suffer. B12 is also critical for methylation processes that influence mood, detox pathways and neurotransmitter balance.

Q: What does Vitamin B12 do in the body on a daily basis?
A: On a daily level, Vitamin B12 supports energy metabolism, maintains nerve insulation (myelin), assists in the production of neurotransmitters, and helps regulate homocysteine levels. It works closely with folate and vitamin B6 to keep methylation cycles functioning efficiently, which affects everything from mental clarity to cardiovascular health.

Q: What are the main symptoms of not having enough Vitamin B12?
A: Symptoms of B12 deficiency can be wide ranging and often subtle at first. Common signs include extreme tiredness, low energy, weakness, pins and needles (paraesthesia), numbness in hands or feet, a sore or inflamed tongue, mouth ulcers, pale or jaundiced skin, shortness of breath, and disturbed vision. Neurological and psychological symptoms may include poor memory, brain fog, low mood, anxiety, confusion and difficulty concentrating. Long term deficiency can lead to nerve damage.

Q: What is the most common cause of Vitamin B12 deficiency?
A: The most common cause is not lack of intake, but poor absorption. Vitamin B12 absorption depends on adequate stomach acid and intrinsic factor, both of which decline with age, stress, medication use and digestive imbalance. Conditions affecting the stomach or gut, chronic stress, low hydrochloric acid, and autoimmune conditions can all impair B12 uptake even when dietary intake appears sufficient.

Q: Can diet alone provide enough Vitamin B12?
A: While B12 is found naturally in animal foods such as meat, fish, eggs and dairy, modern farming practices, food processing and individual digestive capacity mean that dietary intake does not always translate into usable B12. Vegans and vegetarians are at higher risk, but many omnivores also develop deficiency due to absorption issues rather than intake alone.

Q: Why is Vitamin B12 deficiency so common today?
A: Modern life places a high demand on B12. Chronic stress, alcohol use, digestive disorders, ageing, medications (such as antacids and metformin), and reduced stomach acid all impair absorption. Additionally, increased neurological and cognitive demand increases B12 utilisation, meaning requirements may be higher than in previous generations.

Q: What makes Perque Activated B-12 different from standard B12 supplements?
A: Perque Activated B-12 uses hydroxocobalamin, a parent form of B12 with a longer half life in the body. Unlike cyanocobalamin or isolated methyl forms, hydroxocobalamin allows the body to convert B12 into active forms as needed, supporting balance rather than forcing a single biochemical pathway.

Q: Why is hydroxocobalamin considered a superior form of Vitamin B12?
A: Hydroxocobalamin remains in circulation longer than other forms and has been shown to raise and sustain serum B12 levels effectively. It is well tolerated, highly versatile and suitable for individuals sensitive to methylated supplements. It also supports detox pathways by binding nitric oxide and supporting healthy methylation.

Q: Why is this B12 delivered as a lozenge?
A: The lozenge format allows Vitamin B12 to be absorbed directly through the oral mucosa, bypassing the stomach and intrinsic factor requirement. This makes it ideal for individuals with digestive challenges, low stomach acid or impaired absorption. It is often referred to as an “oral injection” due to its efficiency.

Q: Is this form comparable to B12 injections?
A: Studies on Perque Activated B-12 Guard lozenges have shown absorption levels approaching those of injectable B12, without the need for needles. For many people, this makes it a highly effective and convenient alternative.

Q: Who may benefit most from Perque Activated B-12 Guard?
A: This product is particularly useful for individuals experiencing fatigue, brain fog, low energy, neurological strain, digestive issues, high stress, or increased cognitive demand. It is also beneficial for vegans, vegetarians, older adults and anyone with known absorption challenges.

Q: How often should I take Activated B-12 Guard?
A: For most people, one lozenge daily is sufficient. Because hydroxocobalamin has a long half life, it provides sustained support rather than short bursts of stimulation.

Q: Can Vitamin B12 support mental clarity and mood?
A: Yes. Vitamin B12 is involved in the production of neurotransmitters and supports SAMe activity, which plays a role in mood regulation, focus and mental resilience. Adequate B12 levels are associated with improved cognitive performance and emotional balance.

Q: Is Perque Activated B-12 Guard suitable for long term use?
A: Yes. It is designed for safe, daily, long term use and contains no inactive ingredients or unnecessary fillers. It supports foundational physiology rather than acting as a stimulant.

• As a dietary supplement‚ take one (1) sublingual lozenge daily or take it as directed by your healthcare professional. Place one lozenge under tongue and let dissolve. Do not exceed the recommended daily intake.

WARNING: Pregnant and nursing mothers need to check with their health professional before taking supplements.

• Vitamin B12 (as hydroxocobalamin) 2000 mcg.
• Mannitol 295mg. 
• Cane juice (whole organic) 1mg. 
• Whole Cherry fruit extract 3.5mg. 
• Raspberry flavour 8.5mg.
• Croscarmellose (Vegetable fibre) 25mg.
• Magnesium C16 & C18 alkyls 3.5mg

• Brand: Perque.
• Form: Lozenges.
• Quantity: 100.
• Storage: Keep in a cool dry place, keep out of reach of children.
• Estimated shelf life from purchase: 1 - 2 years.