Colloidal Silver

Q: How does particle size and ppm affect the effectiveness of Colloidal Silver?
A: Smaller particles (typically 10 to 20 PPM) have a greater surface area and are thought to interact more efficiently with microbes, while PPM (parts per million) indicates concentration. High PPM isn’t always better, since overly concentrated silver may clump and be less bioavailable. We have used this Silver since 2010 and everyone was happy. If it ain't broke...

Q: Can Colloidal Silver cross the blood-brain barrier, and what are the implications?
A: Very small silver nanoparticles may cross the blood-brain barrier. This raises both potential interest for neuroprotective or antimicrobial applications in the brain, but also concerns about accumulation and long-term safety. We are legally not able to sell Colloidal Silver as an internal supplement so cannot advise further.

Q: How does Colloidal Silver interact with the gut microbiome?
A: It may reduce pathogenic bacteria, but it can also disturb beneficial gut flora if used excessively. Smart biohackers often cycle or microdose Colloidal Silver rather than continuous use, and combine with probiotics.

Q: Is there a hormetic effect from low-dose silver exposure?
A: Some researchers suggest very low levels may act as a mild stressor that upregulates antioxidant defences, though this area is still underexplored in humans.

Q: Can Colloidal Silver be used topically in ways that differ from oral use?
A: Yes. Topical application may reduce skin infections, support wound healing, or calm inflammatory skin conditions without the systemic risks associated with oral intake. Use the spray and dropper for this.

Q: Is topical use of Colloidal Silver functionally safer or less likely to cause systemic risks than oral ingestion?
A: Topical use minimises systemic exposure and is supported in wound care. However, broken skin or mucous membranes can still absorb nanoparticles, especially with repeated use. For systemic biohacking goals, topical-only is unlikely to provide meaningful systemic impact.

Q: How does Colloidal Silver influence oxidative stress markers and mitochondrial function?
A: Silver ions generate reactive oxygen species (ROS) as part of their antimicrobial mechanism. In vitro, this can modulate mitochondrial respiration and increase oxidative load. Some biohackers leverage this as a hormetic stressor, but chronic use could deplete antioxidants (e.g., glutathione). Co-supplementation with our NAC or Liposomal Vitamin C may mitigate risk.

Q: Are there known synergistic effects between colloidal silver and other compounds commonly used in biohacking (e.g., ozone therapy, herbal antimicrobials, peptides)?
A: Yes, Silver nanoparticles show synergistic antimicrobial effects with curcumin, green tea catechins, and ozone, often lowering the dose required of each. However, combining with other ROS-generating hacks could amplify oxidative burden, so antioxidant cycling is advised.

Q: How efficiently does the human body clear nano-silver, and where does it primarily deposit?
A: Clearance is slow. Accumulation primarily occurs in the liver, spleen, and skin. Renal clearance is partial, with larger nanoparticles persisting longer. Chronic overuse can lead to argyria (bluish skin discoloration) but more subtly, long-term tissue deposition is an underexplored risk.

Q: Which genetic or biochemical markers might influence an individual's tolerance or risk to Colloidal Silver?
A: Variants in metallothionein genes (metal-binding proteins), glutathione metabolism efficiency, and CYP pathways may all modulate tolerance. People with poor detox capacity (e.g., GSTM1-null genotype) may accumulate particles more readily.

Q: How does Colloidal Silver compare to ionic silver solutions or silver hydrosols?
A: Ionic silver is often cheaper and less stable, while true Colloidal suspensions provide nanoparticles. Hydrosols are marketed as more bioavailable, but differences in stability, purity, and safety need scrutiny. As I said earlier, we've supplied Colloidal Silver since 2010, it gets results. Companies are always looking to re-invent the wheel or have some unique new product. In my opinion Colloidal Silver is the only one proven over time to consistently get results, it's been around the longest, anything else again in my opinion is a gimmick. Thats not to say they don't work, but probably Colloidal Silver would of worked the same or better.

Q: What precautions reduce the risk of argyria (skin greying)?
A: Avoiding high ppm, poor-quality products, and long-term heavy dosing minimises this risk. True Colloidal Silver with very small particle size, used in moderation, carries far lower risk than ionic silver salts.

Q: Are there synergies between Colloidal Silver and other natural antimicrobials?
A: Colloidal Silver may enhance the effects of herbs like oregano oil, garlic, or berberine, and some studies show it potentiates antibiotics by weakening microbial resistance.

Q: How does Colloidal Silver interact with detox pathways?
A: The body does not actively metabolise silver; it deposits in tissues and is slowly excreted. Supporting detox through glutathione, sulphation, and regular sweating may help minimise accumulation.

Q: How do advanced users typically cycle Colloidal Silver for safety and effect?
A: Biohackers rarely take Colloidal Silver continuously. A common approach is short-term use during acute infection or high exposure risk, then stopping once resolved. Others microdose at low ppm a few days per week and pause regularly to reduce tissue build-up. Cycling with probiotic or gut-supporting phases helps maintain microbial balance while still gaining antimicrobial benefits.

Q: Why would I buy 100ml instead of the 500ml, the cost doesn't make sense?
A: With the 100ml you have the highest quality Miron Glass Bottle there is, a spray to apply topically and a dropper for ears and eyes etc. You can buy a little funnel and always top this bottle up using the large bottle. So you get all you need then just be economical going forward.

Q: Can I use Colloidal Silver on my cat?
A: Colloidal Silver is easy to administer since it doesn't have much of a taste or smell. It can also be used externally as it can be licked by the cat. Many cat owners will put Colloidal Silver on any scratches to help them heal. Colloidal Silver has antibacterial, antifungal, and antimicrobial properties. Since Colloidal Silver may work as a natural antibiotic, it may help to keep pesky infections at bay. Since cats are prone to UTIs and other infections, you may be tired of turning to expensive and potentially harmful remedies such as steroids and antibiotics. These can cause long-term side effects. Colloidal Silver is used by some in a cat's first aid kit as a natural antibiotic.

Q: Where is Colloidal Silver used?
A: Colloidal Silver is approved for topical application on skin infections, skin wounds, and in bandages and dressings for the treatment of burns. 

• Oral Care: Hold Colloidal Silver in your mouth for as long as possible before spitting out.
• Topical Application: Moisten infected area with Silver (use cotton swab) for a minimum of 10 minutes per treatment. Apply 3 times a day and increase/decrease frequency as needed. Tailor the dosage to relieve the symptoms. On boils, warts, and cold sores apply a saturated cotton ball over desired area and apply a bandage. For skin tags apply Lugol’s Iodine.
• Ears: For ears start with a few drops 2-3 times per day, and see how you get on, duration of dose and amount to be delivered will vary depending on the person and issue. For eyewash apply 5 - 7 drops.
• Nebuliser: Nebulising Silver is fantastic way to deliver the great benefits of Silver to the respiratory system. Simply add 5ml of Silver to the Nebuliser and use for as long as you like.
• Dog Care: Colloidal Silver is a natural antibiotic that has been circulating in societies for centuries. It was initially used by both the Romans and the Greeks as a way to keep themselves healthy. It comes in a liquid form, and though it was first used amongst humans, it is evident that dogs can benefit from this “supplement” as well. In general, Ancient Purity Colloidal Silver is a powerful solution that can kill a vast range of bacteria, fungi, viruses, skin irritations, and infections. The submicroscopic elements within the Colloidal Silver are so small, that it is able to penetrate through cells in the body, and eliminate the unwanted pathogens (damaging their ability to metabolise oxygen) to improve the health of your pup.   2 to 3 times daily. For smaller dogs, we recommended a dosage of 5 ml (or up to 5 drops) 2 to 3 times daily. We highly recommend reading some of the many articles available about Colloidal Silver online. You should speak to your healthcare practitioner about its use and decide what’s best for you. The future of health keeps involving and we have to educate ourselves keeping on top of new developments. Ancient Purity happily shares their experiences with others while always taking and respecting the advice of medical professionals.

• Colloidal Silver 10 - 20ppm.

• Brand: Ancient Purity.
• Size: 100ml - Sprayer / Dropper | 500ml - Bottle.
• Particle size: 10-20 PPM.
• Origin: England.
• Container: Miron Glass / Amber Glass bottle.
• Estimated shelf life from purchase: 2-4 years.
• Storage: Your Silver will be supplied in a dark glass bottle, but please also keep it in a cupboard out of sunlight, to harness its full benefits. Store at a cool temperature but not refrigerated or frozen.