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Bowel Calm (Saccharomyces boulardii)

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Bowel Calm (Saccharomyces boulardii)

80 Capsules
A pure Saccharomyces boulardii supplement. An extensively researched microorganism, proven to reach the gut alive. A capsule provides 5 billion live cultures of pure, shelf stable Saccharomyces boulardii. This strain has been internationally acclaimed as a well-researched and unique microorganism, and has been safely used for the last 50 years. Saccharomyces boulardii is a natural food supplement, and not a medicine.

Availability: In stock

£28.99

Details22

Saccharomyces boulardii is a natural and safe microorganism with vast scientific research and documentation. This strain has been internationally acclaimed as a well-researched and unique microorganism, and has been safely used for the last 50 years. Saccharomyces boulardii is a natural food supplement, and not a medicine.

Saccharomyces boulardii is a unique microorganism which is sold widely in the US, Scandinavia, Germany & France. This microorganism is more robust to environmental stressors than more common bacterial live cultures, and shows strong resistance to heat, humidity and stomach acidity levels. These live cultures of S. boulardii have been tested and shown to be especially stable and resistant.

Saccharomyces boulardii contains 5 billion live microorganisms of pure Saccharomyces boulardiiprobiotic guaranteed per capsule.

Clinical Research on Saccharomyces boulardii and diarrhoea

McFarland, L.V. & Bernasconi, P. (1993) Saccharomyces boulardii: A Review of an Innovative Biotherapeutic Agent. Microbial Ecology in Health and Disease; Vol. 6 pp. 157-171.

Hochter, W. et al (1990) Saccharomyces boulardii in acute adult diarrhea. Efficacy and tolerance of treatment. Munchener Medizinische Wochenschrift; Vol. 132 (12) pp. 188-192.

Cetina-Sauri, G. & Basto, S. (1994) Therapeutic evaluation of Saccharomyces boulardii in children with acute diarrhea. Annales de Pediatrie; Vol. 41 (6) pp. 397-400.

Kurugol, Z. & Koturoglu, G. (2005) Effects of Saccharomyces boulardii in children with acute diarrhea. Acta Paediatrica; Vol. 94 pp. 44-47.

Maupas, J.L. et al. (1983) Treatment of Irritable Bowel Syndrome (IBS) Double Blind Trial of Saccharomyces boulardii. Medecine Chirurgie Digestives. Vol. 12 (1) pp. 77 – 79.

Kotowska, M. et al. (2005)Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea in children: a randomized double-blind placebo-controlled trial. Alimentary Pharmacology & Therapeutics 21 (5), 583–590

Erdeve, O. et al. (2004) 'The probiotic effect of S.boulardii in a pediatric age group' Journal of Trop Pediatr. Aug;50(4) pp.234-6

D'Souza, A. et al. (2002) Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis. Care of the Elderly Section, Faculty of Medicine, Imperial College School of Medicine, Hammersmith Hospital, London. BMJ 2002;324:1361 ( 8 June )

Kirchhelle, A. et al. (1996) Treatment of persistent diarrhoea with Saccharomyces boulardii in returning travellers. Results of a prospective study; Fortschr Med; Vol. 114 (11) pp. 136-140

Grandy, G. et al. (2010) Probiotics in the treatment of acute rotavirus diarrhoea. A randomized, double-blind, controlled trial using two different probiotic preparations in Bolivian children; BMC Infectious Diseases, Vol. 10 pp. 253

Clinical Research on Saccharomyces boulardii and Candida

Ducluzeau, R. & Bensaada, M. (1982) Comparative effect of a single or continuous administration of Saccharomyces boulardii on the establishment of various strains of Candida in the digestive tract of gnotobiotic mice. Annales de microbiologie. (Inst. Pasteur). 133: pp: 491-501

Jawhara, S. & Poulain, D. (2007) Saccharomyces boulardii decreases inflammation and intestinal colonisation by Candida albicans in a mouse model of chemically-induced colitis. Medical Mycology, Vol. 45. Issue 8. pp 691 - 700.

Berg, R. et al. (1993) Inhibition of Candida albicans translocation from the gastrointestinal tract of mice by oral administration of Saccharomcyes boulardii. J Infect Dis. 1993,Nov;168(5):1314-8.

Murzyn, et al. (2010) Capric Acid Secreted by S. boulardii Inhibits C. Albicans. August 2010, Plos One, Vol. 5. Issue 8.

Clinical Research on Saccharomyces boulardii and Clostridium difficile disease

McFarland, L.V. et al. (1994) A randomised placebo-controlled trial of saccharomyces boulardii in combination with standard antibiotics for clostridium difficile disease. The Journal of the American Medical Association. Vol. 271. pp. 1913 - 1918

Surawicz, C.M. et al (2000) The Search for a Better Treatment for Recurrent Clostridium difficile Disease: Use of High-Dose Vancomycin Combined with Saccharomyces boulardii. Clinical Infectious Diseases. Vol. 31 pp. 1012 – 1017

Buts, J. et al. (1993) Saccharomyces boulardii for Clostridium difficile-Associated Enteropathies in Infants. Journal of Pediatric Gastroenterology and Nutrition. Vol. 16 pp. 419 – 425

Surawicz, C.M. et al. (1989) Treatment of Recurrent Clostridium difficile Colitis with Vancomycin and Saccharomyces boulardii. The American Journal of Gastroenterology. Vol. 85 (10)

Surawicz, C.M. (2003) Probiotics, antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in humans. Best Practice & Research Clinical Gastroenterology. Vol. 17 (5) pp. 775 – 783

Castagliuolo, I. et al. (1999) Saccharomyces boulardii protease inhibits the effects of Clostridium difficiletoxins A and B in human colonic mucosa. Infect Immun. 67(I): 302 - 307.

Pothoulakis, C. et al. (1993) Saccharomyces boulardii inhibits Clostridium difficile toxin: A binding and enterotoxicity in rat ileum. Gastroenterology: 104(4): 1108 - 1115.

Tung, J.M et al. (2010) Prevention of Clostridium difficile with Saccharomyces boulardii: A systematic review; Canadian Journal of Gastroenterology, Vol. 23(12) pp. 817-821

Clinical Research on Saccharomyces boulardii and Inflammatory Bowel Disease

Guslandi, M. et al. (2000) Saccharomyces boulardii in Maintenance Treatment of Crohn's Disease. Digestive Diseases & Sciences. Vol 45, 7, 1462 - 1464.

Guslandi, M. et al. (2003) A pilot trial of Saccharomyces boulardii in ulcerative colitis. European Journal of Gastroenterology & Hepatology. Vol. 15 pp. 697 – 698.

disclaimer

Details44

  • Live cultures: Saccharomyces boulardii (250mg); vegetarian capsule: hydroxypropyl methylcellulose; filler: potato starch; lubricant: magnesium stearate; antiadherant: silicon dioxide.
  • Each capsule guarantees 5 billion live cultures.

Details44

Saccharomyces boulardii can be given to adults and children (from 1 year and over) with the following recommendations, or as professionally directed.

  • Take one to four capsules depending on severity of symptoms and up to six capsules daily, or as professionally directed
  • If taking anti-fungals, take separately (at least 2 hours apart).
  • For infants and children the dose should be lowered
  • Drink plenty of water with your course of live cultures. 
  • For anyone unable to swallow capsules, capsule can be opened and contents mixed with a cold meal or beverage. 

Safety: Live cultures are not recommended for those with serious medical conditions eg. those who are severely immunosuppressed, have pancreatitis, are in the ICU, have melaena, have a central venous catheter, infants with short bowel syndrome, or to patients with open wounds following major surgery; unless under a doctor's care. Furthermore, pregnant or breastfeeding women should consult their doctor before taking Saccharomyces boulardii, 'For travelling abroad', or natural plant extracts as in 'For daily immunity'.

ANTI-CANDIDA Protocol.
Gradually build up to 3 caps twice a day (daily dose: 6 Caps) Initially, we recommend taking 1 capsule twice a day in the first week, 2 caps twice a day in the second week and 3 Caps twice a day in the thrid week. This gradual build up in dosage is to avoid severe "die off". Take alongside 1-2 Caps of Extra Strength Probiotics. 

Details44

  • Size: 250mg
  • Quantity: 80 Capsules
  • Container: Plastic tub (in box) 
  • Estimated shelf life from purchase: 2 years. 
  • Storage: Keep in a cool dry place, out of sunlight.This probiotic does not require refrigeration.
  • Suitable for vegans & vegetarians.

Saccharomyces boulardii is a unique yeast and microorganism. This strain from OptiBac Probiotics is scientifically proven to reach the gut alive.


VegetarianVegetarian
No DairyNo Dairy
No GlutenNo Gluten
Suitable during PregnancySuitable during Pregnancy

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